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TBK1 Limits mTORC1 by Promoting Phosphorylation of Raptor Ser877
While best known for its role in the innate immune system, the TANK-binding kinase 1 (TBK1) is now known to play a role in modulating cellular growth and autophagy. One of the major ways that TBK1 accomplishes this task is by modulating the mechanistic Target of Rapamycin (mTOR), a master regulator...
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| Опубликовано в: : | Sci Rep |
|---|---|
| Главные авторы: | , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Publishing Group UK
2019
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6748941/ https://ncbi.nlm.nih.gov/pubmed/31530866 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-49707-8 |
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