The anti-parasitic drug suramin potently inhibits formation of seminal amyloid fibrils and their interaction with HIV-1

Seminal amyloid fibrils are made up of naturally occurring peptide fragments and are key targets for the development of combination microbicides or antiviral drugs. Previously, we reported that the polysulfonic compound ADS-J1 is a potential candidate microbicide that not only inhibits HIV-1 entry,...

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Bibliographic Details
Published in:J Biol Chem
Main Authors: Tan, Suiyi, Li, Jin-Qing, Cheng, Hongyan, Li, Zhaofeng, Lan, Yan, Zhang, Ting-Ting, Yang, Zi-Chao, Li, Wenjuan, Qi, Tao, Qiu, Yu-Rong, Chen, Zhipeng, Li, Lin, Liu, Shu-wen
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2019
Subjects:
Microbiology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6746445/
https://ncbi.nlm.nih.gov/pubmed/31346035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.006797
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