The anti-parasitic drug suramin potently inhibits formation of seminal amyloid fibrils and their interaction with HIV-1

Seminal amyloid fibrils are made up of naturally occurring peptide fragments and are key targets for the development of combination microbicides or antiviral drugs. Previously, we reported that the polysulfonic compound ADS-J1 is a potential candidate microbicide that not only inhibits HIV-1 entry,...

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Dades bibliogràfiques
Publicat a:J Biol Chem
Autors principals: Tan, Suiyi, Li, Jin-Qing, Cheng, Hongyan, Li, Zhaofeng, Lan, Yan, Zhang, Ting-Ting, Yang, Zi-Chao, Li, Wenjuan, Qi, Tao, Qiu, Yu-Rong, Chen, Zhipeng, Li, Lin, Liu, Shu-wen
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2019
Matèries:
Microbiology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6746445/
https://ncbi.nlm.nih.gov/pubmed/31346035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.006797
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