The anti-parasitic drug suramin potently inhibits formation of seminal amyloid fibrils and their interaction with HIV-1

Seminal amyloid fibrils are made up of naturally occurring peptide fragments and are key targets for the development of combination microbicides or antiviral drugs. Previously, we reported that the polysulfonic compound ADS-J1 is a potential candidate microbicide that not only inhibits HIV-1 entry,...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:J Biol Chem
Main Authors: Tan, Suiyi, Li, Jin-Qing, Cheng, Hongyan, Li, Zhaofeng, Lan, Yan, Zhang, Ting-Ting, Yang, Zi-Chao, Li, Wenjuan, Qi, Tao, Qiu, Yu-Rong, Chen, Zhipeng, Li, Lin, Liu, Shu-wen
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2019
Teme:
Microbiology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6746445/
https://ncbi.nlm.nih.gov/pubmed/31346035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.006797
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