ADS-J1 Inhibits Semen-Derived Amyloid Fibril Formation and Blocks Fibril-Mediated Enhancement of HIV-1 Infection

Semen-derived enhancer of viral infection (SEVI) is composed of amyloid fibrils that can greatly enhance HIV-1 infectivity. By its cationic property, SEVI promotes viral sexual transmission by facilitating the attachment and internalization of HIV-1 to target cells. Therefore, semen-derived amyloid...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Xun, Tianrong, Li, Wenjuan, Chen, Jinquan, Yu, Fei, Xu, Wei, Wang, Qian, Yu, Ruizhe, Li, Xiaojuan, Zhou, Xuefeng, Lu, Lu, Jiang, Shibo, Li, Lin, Tan, Suiyi, Liu, Shuwen
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4538458/
https://ncbi.nlm.nih.gov/pubmed/26055369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00385-15
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