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Marburg virus regulates the IRE1/XBP1-dependent unfolded protein response to ensure efficient viral replication

Viruses regulate cellular signalling pathways to ensure optimal viral replication. During Marburg virus (MARV) infection, large quantities of the viral glycoprotein GP are produced in the ER; this may result in the activation of the unfolded protein response (UPR). The most conserved pathway to trig...

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Détails bibliographiques
Publié dans:Emerg Microbes Infect
Auteurs principaux: Rohde, Cornelius, Becker, Stephan, Krähling, Verena
Format: Artigo
Langue:Inglês
Publié: Taylor & Francis 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6746283/
https://ncbi.nlm.nih.gov/pubmed/31495285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/22221751.2019.1659552
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