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High-plex predictive marker discovery for melanoma immunotherapy treated patients using Digital Spatial Profiling

BACKGROUND: Protein expression in formalin-fixed, paraffin-embedded (FFPE) tissue is routinely measured by immunohistochemistry (IHC) or quantitative fluorescence (QIF) on a handful of markers on a single section. Digital Spatial Profiling (DSP) allows spatially-informed simultaneous assessment of m...

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Detalhes bibliográficos
Publicado no:Clin Cancer Res
Main Authors: Toki, Maria I., Merritt, Christopher R., Wong, Pok Fai, Smithy, James, Kluger, Harriet, Syrigos, Konstantinos, Ong, Giang T., Warren, Sarah E., Beechem, Joseph M., Rimm, David L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6744974/
https://ncbi.nlm.nih.gov/pubmed/31189645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-19-0104
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