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Models that combine transcriptomic with spatial protein information exceed the predictive value for either single modality

Immunotherapy has reshaped the field of cancer therapeutics but the population that benefits are small in many tumor types, warranting a companion diagnostic test. While immunohistochemistry (IHC) for programmed death-ligand 1 (PD-L1) or mismatch repair (MMR) and polymerase chain reaction (PCR) for...

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Bibliografische gegevens
Gepubliceerd in:NPJ Precis Oncol
Hoofdauteurs: Vathiotis, Ioannis A., Yang, Zhi, Reeves, Jason, Toki, Maria, Aung, Thazin Nwe, Wong, Pok Fai, Kluger, Harriet, Syrigos, Konstantinos N., Warren, Sarah, Rimm, David L.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2021
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8163775/
https://ncbi.nlm.nih.gov/pubmed/34050252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41698-021-00184-1
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