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A binding motif for Hsp90 in the A chains of ADP-ribosylating toxins that move from the endoplasmic reticulum to the cytosol

Cholera toxin (Ctx) is an AB-type protein toxin that acts as an ADP-ribosyltransferase to disrupt intracellular signaling in the target cell. It moves by vesicle carriers from the cell surface to the endoplasmic reticulum (ER) of an intoxicated cell. The catalytic CtxA1 subunit then dissociates from...

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Détails bibliographiques
Publié dans:Cell Microbiol
Auteurs principaux: Kellner, Alisha, Taylor, Michael, Banerjee, Tuhina, Britt, Christopher B.T., Teter, Ken
Format: Artigo
Langue:Inglês
Publié: 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6744307/
https://ncbi.nlm.nih.gov/pubmed/31231933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cmi.13074
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