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HSC70 and HSP90 chaperones perform complementary roles in translocation of the cholera toxin A1 subunit from the endoplasmic reticulum to the cytosol

Cholera toxin (CT) travels by vesicle carriers from the cell surface to the endoplasmic reticulum (ER) where the catalytic A1 subunit of CT (CTA1) dissociates from the rest of the toxin, unfolds, and moves through a membrane-spanning translocon pore to reach the cytosol. Heat shock protein 90 (HSP90...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Burress, Helen, Kellner, Alisha, Guyette, Jessica, Tatulian, Suren A., Teter, Ken
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6690686/
https://ncbi.nlm.nih.gov/pubmed/31221799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.008568
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