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Co- and Post-translocation Roles for HSP90 in Cholera Intoxication

Cholera toxin (CT) moves from the cell surface to the endoplasmic reticulum (ER) where the catalytic CTA1 subunit separates from the rest of the toxin. CTA1 then unfolds and passes through an ER translocon pore to reach its cytosolic target. Due to its intrinsic instability, cytosolic CTA1 must be r...

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Библиографические подробности
Опубликовано в: :J Biol Chem
Главные авторы: Burress, Helen, Taylor, Michael, Banerjee, Tuhina, Tatulian, Suren A., Teter, Ken
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Biochemistry and Molecular Biology 2014
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4246115/
https://ncbi.nlm.nih.gov/pubmed/25320090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.609800
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