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Co- and Post-translocation Roles for HSP90 in Cholera Intoxication

Cholera toxin (CT) moves from the cell surface to the endoplasmic reticulum (ER) where the catalytic CTA1 subunit separates from the rest of the toxin. CTA1 then unfolds and passes through an ER translocon pore to reach its cytosolic target. Due to its intrinsic instability, cytosolic CTA1 must be r...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Burress, Helen, Taylor, Michael, Banerjee, Tuhina, Tatulian, Suren A., Teter, Ken
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4246115/
https://ncbi.nlm.nih.gov/pubmed/25320090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.609800
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