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A binding motif for Hsp90 in the A chains of ADP-ribosylating toxins that move from the endoplasmic reticulum to the cytosol
Cholera toxin (Ctx) is an AB-type protein toxin that acts as an ADP-ribosyltransferase to disrupt intracellular signaling in the target cell. It moves by vesicle carriers from the cell surface to the endoplasmic reticulum (ER) of an intoxicated cell. The catalytic CtxA1 subunit then dissociates from...
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| Publicado no: | Cell Microbiol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6744307/ https://ncbi.nlm.nih.gov/pubmed/31231933 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cmi.13074 |
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