Hsp90 Is Required for Transfer of the Cholera Toxin A1 Subunit from the Endoplasmic Reticulum to the Cytosol

Cholera toxin (CT) is an AB(5) toxin that moves from the cell surface to the endoplasmic reticulum (ER) by retrograde vesicular transport. In the ER, the catalytic A1 subunit dissociates from the rest of the toxin and enters the cytosol by exploiting the quality control system of ER-associated degra...

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Autores principales: Taylor, Michael, Navarro-Garcia, Fernando, Huerta, Jazmin, Burress, Helen, Massey, Shane, Ireton, Keith, Teter, Ken
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2010
Materias:
Microbiology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2951200/
https://ncbi.nlm.nih.gov/pubmed/20667832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.148981
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