Structural and Functional Interactions between the Cholera Toxin A1 Subunit and ERdj3/HEDJ, a Chaperone of the Endoplasmic Reticulum

Cholera toxin (CT) is endocytosed and transported by vesicle carriers to the endoplasmic reticulum (ER). The catalytic CTA1 subunit then crosses the ER membrane and enters the cytosol, where it interacts with its Gsα target. The CTA1 membrane transversal involves the ER chaperone BiP, but few other...

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Detalhes bibliográficos
Main Authors: Massey, Shane, Burress, Helen, Taylor, Michael, Nemec, Kathleen N., Ray, Supriyo, Haslam, David B., Teter, Ken
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3257931/
https://ncbi.nlm.nih.gov/pubmed/21844235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.05503-11
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