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Toxin Instability and Its Role in Toxin Translocation from the Endoplasmic Reticulum to the Cytosol
AB toxins enter a host cell by receptor-mediated endocytosis. The catalytic A chain then crosses the endosome or endoplasmic reticulum (ER) membrane to reach its cytosolic target. Dissociation of the A chain from the cell-binding B chain occurs before or during translocation to the cytosol, and only...
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| Autor principal: | |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
MDPI
2013
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4030972/ https://ncbi.nlm.nih.gov/pubmed/24970201 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom3040997 |
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