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Toxin Instability and Its Role in Toxin Translocation from the Endoplasmic Reticulum to the Cytosol

AB toxins enter a host cell by receptor-mediated endocytosis. The catalytic A chain then crosses the endosome or endoplasmic reticulum (ER) membrane to reach its cytosolic target. Dissociation of the A chain from the cell-binding B chain occurs before or during translocation to the cytosol, and only...

詳細記述

保存先:
書誌詳細
第一著者: Teter, Ken
フォーマット: Artigo
言語:Inglês
出版事項: MDPI 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4030972/
https://ncbi.nlm.nih.gov/pubmed/24970201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom3040997
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