Rho-Associated Coiled-Coil Kinase 1 Translocates to the Nucleus and Inhibits Human Cytomegalovirus Propagation

Rho-associated coiled-coil kinase (ROCK) protein is a central kinase that regulates numerous cellular functions, including cellular polarity, motility, proliferation, and apoptosis. Here, we demonstrate that ROCK has antiviral properties, and inhibition of its activity results in enhanced propagatio...

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Bibliografiske detaljer
Udgivet i:J Virol
Main Authors: Eliyahu, Erez, Tirosh, Osnat, Dobesova, Martina, Nachshon, Aharon, Schwartz, Michal, Stern-Ginossar, Noam
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2019
Fag:
Virus-Cell Interactions
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6744247/
https://ncbi.nlm.nih.gov/pubmed/31292242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00453-19
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