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Rho-Associated Coiled-Coil Kinase 1 Translocates to the Nucleus and Inhibits Human Cytomegalovirus Propagation

Rho-associated coiled-coil kinase (ROCK) protein is a central kinase that regulates numerous cellular functions, including cellular polarity, motility, proliferation, and apoptosis. Here, we demonstrate that ROCK has antiviral properties, and inhibition of its activity results in enhanced propagatio...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Eliyahu, Erez, Tirosh, Osnat, Dobesova, Martina, Nachshon, Aharon, Schwartz, Michal, Stern-Ginossar, Noam
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6744247/
https://ncbi.nlm.nih.gov/pubmed/31292242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00453-19
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