Rho-Associated Coiled-Coil Kinase 1 Translocates to the Nucleus and Inhibits Human Cytomegalovirus Propagation

Rho-associated coiled-coil kinase (ROCK) protein is a central kinase that regulates numerous cellular functions, including cellular polarity, motility, proliferation, and apoptosis. Here, we demonstrate that ROCK has antiviral properties, and inhibition of its activity results in enhanced propagatio...

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Bibliografski detalji
Izdano u:J Virol
Glavni autori: Eliyahu, Erez, Tirosh, Osnat, Dobesova, Martina, Nachshon, Aharon, Schwartz, Michal, Stern-Ginossar, Noam
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2019
Teme:
Virus-Cell Interactions
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6744247/
https://ncbi.nlm.nih.gov/pubmed/31292242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00453-19
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