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Rho-Associated Coiled-Coil Kinase 1 Translocates to the Nucleus and Inhibits Human Cytomegalovirus Propagation

Rho-associated coiled-coil kinase (ROCK) protein is a central kinase that regulates numerous cellular functions, including cellular polarity, motility, proliferation, and apoptosis. Here, we demonstrate that ROCK has antiviral properties, and inhibition of its activity results in enhanced propagatio...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:J Virol
Päätekijät: Eliyahu, Erez, Tirosh, Osnat, Dobesova, Martina, Nachshon, Aharon, Schwartz, Michal, Stern-Ginossar, Noam
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 2019
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6744247/
https://ncbi.nlm.nih.gov/pubmed/31292242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00453-19
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