Defining the Transcriptional Landscape during Cytomegalovirus Latency with Single-Cell RNA Sequencing

Primary infection with human cytomegalovirus (HCMV) results in a lifelong infection due to its ability to establish latent infection, with one characterized viral reservoir being hematopoietic cells. Although reactivation from latency causes serious disease in immunocompromised individuals, our mole...

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Veröffentlicht in:mBio
Hauptverfasser: Shnayder, Miri, Nachshon, Aharon, Krishna, Benjamin, Poole, Emma, Boshkov, Alina, Binyamin, Amit, Maza, Itay, Sinclair, John, Schwartz, Michal, Stern-Ginossar, Noam
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2018
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5850328/
https://ncbi.nlm.nih.gov/pubmed/29535194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00013-18
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