Rho-Associated Coiled-Coil Kinase 1 Translocates to the Nucleus and Inhibits Human Cytomegalovirus Propagation

Rho-associated coiled-coil kinase (ROCK) protein is a central kinase that regulates numerous cellular functions, including cellular polarity, motility, proliferation, and apoptosis. Here, we demonstrate that ROCK has antiviral properties, and inhibition of its activity results in enhanced propagatio...

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Библиографические подробности
Опубликовано в: :J Virol
Главные авторы: Eliyahu, Erez, Tirosh, Osnat, Dobesova, Martina, Nachshon, Aharon, Schwartz, Michal, Stern-Ginossar, Noam
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2019
Предметы:
Virus-Cell Interactions
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6744247/
https://ncbi.nlm.nih.gov/pubmed/31292242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00453-19
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