Upgraded molecular models of the human KCNQ1 potassium channel

The voltage-gated potassium channel KCNQ1 (K(V)7.1) assembles with the KCNE1 accessory protein to generate the slow delayed rectifier current, I(KS), which is critical for membrane repolarization as part of the cardiac action potential. Loss-of-function (LOF) mutations in KCNQ1 are the most common c...

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Publicat a:PLoS One
Autors principals: Kuenze, Georg, Duran, Amanda M., Woods, Hope, Brewer, Kathryn R., McDonald, Eli Fritz, Vanoye, Carlos G., George, Alfred L., Sanders, Charles R., Meiler, Jens
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2019
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6743773/
https://ncbi.nlm.nih.gov/pubmed/31518351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0220415
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