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Structures Illuminate Cardiac Ion Channel Functions in Health and in Long QT Syndrome

The cardiac action potential is critical to the production of a synchronized heartbeat. This electrical impulse is governed by the intricate activity of cardiac ion channels, among them the cardiac voltage-gated potassium (K(v)) channels KCNQ1 and hERG as well as the voltage-gated sodium (Na(v)) cha...

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Vydáno v:Front Pharmacol
Hlavní autoři: Brewer, Kathryn R., Kuenze, Georg, Vanoye, Carlos G., George, Alfred L., Meiler, Jens, Sanders, Charles R.
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7212895/
https://ncbi.nlm.nih.gov/pubmed/32431610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.00550
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