Upgraded molecular models of the human KCNQ1 potassium channel

The voltage-gated potassium channel KCNQ1 (K(V)7.1) assembles with the KCNE1 accessory protein to generate the slow delayed rectifier current, I(KS), which is critical for membrane repolarization as part of the cardiac action potential. Loss-of-function (LOF) mutations in KCNQ1 are the most common c...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Kuenze, Georg, Duran, Amanda M., Woods, Hope, Brewer, Kathryn R., McDonald, Eli Fritz, Vanoye, Carlos G., George, Alfred L., Sanders, Charles R., Meiler, Jens
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6743773/
https://ncbi.nlm.nih.gov/pubmed/31518351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0220415
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