Upgraded molecular models of the human KCNQ1 potassium channel

The voltage-gated potassium channel KCNQ1 (K(V)7.1) assembles with the KCNE1 accessory protein to generate the slow delayed rectifier current, I(KS), which is critical for membrane repolarization as part of the cardiac action potential. Loss-of-function (LOF) mutations in KCNQ1 are the most common c...

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Detalles Bibliográficos
Publicado en:PLoS One
Autores principales: Kuenze, Georg, Duran, Amanda M., Woods, Hope, Brewer, Kathryn R., McDonald, Eli Fritz, Vanoye, Carlos G., George, Alfred L., Sanders, Charles R., Meiler, Jens
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6743773/
https://ncbi.nlm.nih.gov/pubmed/31518351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0220415
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