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Characterization and Crystal Structure of a Nonheme Diiron Monooxygenase Involved in Platensimycin and Platencin Biosynthesis

Nonheme diiron monooxygenases make up a rapidly growing family of oxygenases that are rarely identified in secondary metabolism. Herein, we report the in vivo, in vitro, and structural characterizations of a nonheme diiron monooxygenase, PtmU3, that installs a C-5 β-hydroxyl group in the unified bio...

詳細記述

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書誌詳細
出版年:J Am Chem Soc
主要な著者: Dong, Liao-Bin, Liu, Yu-Chen, Cepeda, Alexis J., Kalkreuter, Edward, Deng, Ming-Rong, Rudolf, Jeffrey D., Chang, Changsoo, Joachimiak, Andrzej, Phillips, George N., Shen, Ben
フォーマット: Artigo
言語:Inglês
出版事項: 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6743330/
https://ncbi.nlm.nih.gov/pubmed/31291107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.9b06183
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