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Cryptic and Stereospecific Hydroxylation, Oxidation, and Reduction in Platensimycin and Platencin Biosynthesis

Platensimycin (PTM) and platencin (PTN) are highly functionalized bacterial diterpenoids of ent-kauranol and ent-atiserene biosynthetic origin. C7 oxidation in the B-ring plays a key biosynthetic role in generating structural complexity known for ent-kaurane and ent-atisane derived diterpenoids. Whi...

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Detalhes bibliográficos
Publicado no:J Am Chem Soc
Main Authors: Dong, Liao-Bin, Zhang, Xiao, Rudolf, Jeffrey D., Deng, Ming-Rong, Kalkreuter, Edward, Cepeda, Alexis J., Renata, Hans, Shen, Ben
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6545883/
https://ncbi.nlm.nih.gov/pubmed/30735041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.8b13452
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