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Cryptic and Stereospecific Hydroxylation, Oxidation, and Reduction in Platensimycin and Platencin Biosynthesis

Platensimycin (PTM) and platencin (PTN) are highly functionalized bacterial diterpenoids of ent-kauranol and ent-atiserene biosynthetic origin. C7 oxidation in the B-ring plays a key biosynthetic role in generating structural complexity known for ent-kaurane and ent-atisane derived diterpenoids. Whi...

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Bibliografische gegevens
Gepubliceerd in:J Am Chem Soc
Hoofdauteurs: Dong, Liao-Bin, Zhang, Xiao, Rudolf, Jeffrey D., Deng, Ming-Rong, Kalkreuter, Edward, Cepeda, Alexis J., Renata, Hans, Shen, Ben
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2019
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6545883/
https://ncbi.nlm.nih.gov/pubmed/30735041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.8b13452
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