Catechol-O-Methyltransferase Genotype and Dopamine Regulation in the Human Brain

A functional polymorphism in the gene for catechol-O-methyltransferase (COMT) has been shown to affect executive cognition and the physiology of the prefrontal cortex in humans, probably by affecting prefrontal dopamine signaling. The COMT valine allele, associated with relatively poor prefrontal fu...

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Bibliografske podrobnosti
izdano v:J Neurosci
Main Authors: Akil, Mayada, Kolachana, Bhaskar S., Rothmond, Debora A., Hyde, Thomas M., Weinberger, Daniel R., Kleinman, Joel E.
Format: Artigo
Jezik:Inglês
Izdano: Society for Neuroscience 2003
Teme:
Brief Communication
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6742018/
https://ncbi.nlm.nih.gov/pubmed/12657658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.23-06-02008.2003
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