Catechol-O-Methyltransferase Genotype and Dopamine Regulation in the Human Brain

A functional polymorphism in the gene for catechol-O-methyltransferase (COMT) has been shown to affect executive cognition and the physiology of the prefrontal cortex in humans, probably by affecting prefrontal dopamine signaling. The COMT valine allele, associated with relatively poor prefrontal fu...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Akil, Mayada, Kolachana, Bhaskar S., Rothmond, Debora A., Hyde, Thomas M., Weinberger, Daniel R., Kleinman, Joel E.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2003
Assuntos:
Brief Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6742018/
https://ncbi.nlm.nih.gov/pubmed/12657658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.23-06-02008.2003
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