Catechol-O-Methyltransferase Genotype and Dopamine Regulation in the Human Brain

A functional polymorphism in the gene for catechol-O-methyltransferase (COMT) has been shown to affect executive cognition and the physiology of the prefrontal cortex in humans, probably by affecting prefrontal dopamine signaling. The COMT valine allele, associated with relatively poor prefrontal fu...

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Vydáno v:J Neurosci
Hlavní autoři: Akil, Mayada, Kolachana, Bhaskar S., Rothmond, Debora A., Hyde, Thomas M., Weinberger, Daniel R., Kleinman, Joel E.
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2003
Témata:
Brief Communication
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6742018/
https://ncbi.nlm.nih.gov/pubmed/12657658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.23-06-02008.2003
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