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Catechol-O-Methyltransferase Genotype and Dopamine Regulation in the Human Brain

A functional polymorphism in the gene for catechol-O-methyltransferase (COMT) has been shown to affect executive cognition and the physiology of the prefrontal cortex in humans, probably by affecting prefrontal dopamine signaling. The COMT valine allele, associated with relatively poor prefrontal fu...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Neurosci
Prif Awduron: Akil, Mayada, Kolachana, Bhaskar S., Rothmond, Debora A., Hyde, Thomas M., Weinberger, Daniel R., Kleinman, Joel E.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Society for Neuroscience 2003
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6742018/
https://ncbi.nlm.nih.gov/pubmed/12657658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.23-06-02008.2003
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