Catechol-O-methyltransferase Val(158)Met Genotype and Resting Regional Cerebral Blood Flow in Medication-Free Patients with Schizophrenia

BACKGROUND: A valine(158)methionine polymorphism in Catechol-O-methyltransferase (COMT) modulates cortical dopaminergic catabolism and has been associated with schizophrenia. Consistent with schizophrenia itself, during cognitive tasks, the risk (val) allele predicts less efficient prefrontal cortex...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Eisenberg, Daniel Paul, Sarpal, Deepak, Kohn, Philip D., Meyer-Lindenberg, Andreas, Wint, Dylan, Kolachana, Bhaskar, Apud, José, Weinberger, Daniel R., Berman, Karen Faith
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2812618/
https://ncbi.nlm.nih.gov/pubmed/19892319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2009.08.039
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados