Catechol-O-methyltransferase Val(158)Met Genotype and Resting Regional Cerebral Blood Flow in Medication-Free Patients with Schizophrenia

BACKGROUND: A valine(158)methionine polymorphism in Catechol-O-methyltransferase (COMT) modulates cortical dopaminergic catabolism and has been associated with schizophrenia. Consistent with schizophrenia itself, during cognitive tasks, the risk (val) allele predicts less efficient prefrontal cortex...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Eisenberg, Daniel Paul, Sarpal, Deepak, Kohn, Philip D., Meyer-Lindenberg, Andreas, Wint, Dylan, Kolachana, Bhaskar, Apud, José, Weinberger, Daniel R., Berman, Karen Faith
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2009
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2812618/
https://ncbi.nlm.nih.gov/pubmed/19892319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2009.08.039
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