25. Cortical Information Processing in Patients With Schizophrenia is Modulated by Tolcapone: Role of COMT val158met Genotype

Background: Dopamine (DA) dysfunction is involved in deficits underlying working memory (WM) and prefrontal cortical (PFC) physiology in patients with schizophrenia. Evidence indicates that DA stabilizes and focuses the prefrontal cortical web by modulating NMDA, non-NMDA, and GABAergic networks. Ca...

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Pubblicato in:Schizophr Bull
Autori principali: Apud, Jose, Tong, Yunxia, Rasetti, Roberta, Vargas, Teresa, Callicott, Joseph, Dickinson, Dwight, Kolachana, Bhaskar, Weinberger, Daniel, Mattay, Venkata, Berman, Karen
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2017
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Abstracts
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5475479/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/schbul/sbx021.044
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