25. Cortical Information Processing in Patients With Schizophrenia is Modulated by Tolcapone: Role of COMT val158met Genotype

Background: Dopamine (DA) dysfunction is involved in deficits underlying working memory (WM) and prefrontal cortical (PFC) physiology in patients with schizophrenia. Evidence indicates that DA stabilizes and focuses the prefrontal cortical web by modulating NMDA, non-NMDA, and GABAergic networks. Ca...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Schizophr Bull
Prif Awduron: Apud, Jose, Tong, Yunxia, Rasetti, Roberta, Vargas, Teresa, Callicott, Joseph, Dickinson, Dwight, Kolachana, Bhaskar, Weinberger, Daniel, Mattay, Venkata, Berman, Karen
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2017
Pynciau:
Abstracts
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5475479/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/schbul/sbx021.044
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