Effect of COMT Val(108/158) Met genotype on frontal lobe function and risk for schizophrenia

Abnormalities of prefrontal cortical function are prominent features of schizophrenia and have been associated with genetic risk, suggesting that susceptibility genes for schizophrenia may impact on the molecular mechanisms of prefrontal function. A potential susceptibility mechanism involves regula...

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Detalhes bibliográficos
Main Authors: Egan, Michael F., Goldberg, Terry E., Kolachana, Bhaskar S., Callicott, Joseph H., Mazzanti, Chiara M., Straub, Richard E., Goldman, David, Weinberger, Daniel R.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2001
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC34453/
https://ncbi.nlm.nih.gov/pubmed/11381111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.111134598
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