Reward system neurodynamics during menstrual pain modulated by COMT Val158Met polymorphisms

IntroductionPrimary dysmenorrhea (PDM), characterized by cyclic pain, may involve pain modulation within the reward system (RS). The Catechol-O-methyltransferase (COMT) Val158Met polymorphism, which significantly influences dopamine activity, is linked to the regulation of both acute and chronic pai...

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Hlavní autoři:	Pei-Shan Hsu, Ching-Hsiung Liu, Ching-Ju Yang, Lin-Chien Lee, Wei-Chi Li, Hsiang-Tai Chao, Ming-Wei Lin, Li-Fen Chen, Jen-Chuen Hsieh
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2024-09-01
Edice:	Frontiers in Molecular Neuroscience
Témata:	primary dysmenorrhea COMT Val158Met polymorphism functional magnetic resonance imaging amplitude of low-frequency fluctuation functional connectivity reward system
On-line přístup:	https://www.frontiersin.org/articles/10.3389/fnmol.2024.1457602/full
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