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Mutant Huntingtin Causes Context-Dependent Neurodegeneration in Mice with Huntington's Disease
Huntington's disease (HD) mouse models that express N-terminal huntingtin fragments show rapid disease progression and have been used for developing therapeutics. However, light microscopy reveals no significant neurodegeneration in these mice. It remains unclear how mutant huntingtin induces n...
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| 出版年: | J Neurosci |
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| 主要な著者: | , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Society for Neuroscience
2003
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6742008/ https://ncbi.nlm.nih.gov/pubmed/12657678 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.23-06-02193.2003 |
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