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Huntingtin Aggregate-Associated Axonal Degeneration is an Early Pathological Event in Huntington's Disease Mice

Huntington's disease (HD) is characterized by the selective loss of striatal projection neurons. In early stages of HD, neurodegeneration preferentially occurs in the lateral globus pallidus (LGP) and substantia nigra (SN), two regions in which the axons of striatal neurons terminate. Here we r...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Li, He, Li, Shi-Hua, Yu, Zhao-Xue, Shelbourne, Peggy, Li, Xiao-Jiang
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6762783/
https://ncbi.nlm.nih.gov/pubmed/11606636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.21-21-08473.2001
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