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Computational tools to detect signatures of mutational processes in DNA from tumours: A review and empirical comparison of performance

Mutational signatures refer to patterns in the occurrence of somatic mutations that might be uniquely ascribed to particular mutational process. Tumour mutation catalogues can reveal mutational signatures but are often consistent with the mutation spectra produced by a variety of mutagens. To date,...

詳細記述

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書誌詳細
出版年:PLoS One
主要な著者: Omichessan, Hanane, Severi, Gianluca, Perduca, Vittorio
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6741849/
https://ncbi.nlm.nih.gov/pubmed/31513583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0221235
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