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Computational tools to detect signatures of mutational processes in DNA from tumours: A review and empirical comparison of performance
Mutational signatures refer to patterns in the occurrence of somatic mutations that might be uniquely ascribed to particular mutational process. Tumour mutation catalogues can reveal mutational signatures but are often consistent with the mutation spectra produced by a variety of mutagens. To date,...
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| Pubblicato in: | PLoS One |
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| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Public Library of Science
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6741849/ https://ncbi.nlm.nih.gov/pubmed/31513583 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0221235 |
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