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Computational tools to detect signatures of mutational processes in DNA from tumours: A review and empirical comparison of performance

Mutational signatures refer to patterns in the occurrence of somatic mutations that might be uniquely ascribed to particular mutational process. Tumour mutation catalogues can reveal mutational signatures but are often consistent with the mutation spectra produced by a variety of mutagens. To date,...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:PLoS One
Päätekijät: Omichessan, Hanane, Severi, Gianluca, Perduca, Vittorio
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2019
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6741849/
https://ncbi.nlm.nih.gov/pubmed/31513583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0221235
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