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Computational tools to detect signatures of mutational processes in DNA from tumours: A review and empirical comparison of performance

Mutational signatures refer to patterns in the occurrence of somatic mutations that might be uniquely ascribed to particular mutational process. Tumour mutation catalogues can reveal mutational signatures but are often consistent with the mutation spectra produced by a variety of mutagens. To date,...

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Bibliografische gegevens
Gepubliceerd in:PLoS One
Hoofdauteurs: Omichessan, Hanane, Severi, Gianluca, Perduca, Vittorio
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2019
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6741849/
https://ncbi.nlm.nih.gov/pubmed/31513583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0221235
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