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Computational approaches for discovery of mutational signatures in cancer

The accumulation of somatic mutations in a genome is the result of the activity of one or more mutagenic processes, each of which leaves its own imprint. The study of these DNA fingerprints, termed mutational signatures, holds important potential for furthering our understanding of the causes and ev...

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Detalhes bibliográficos
Publicado no:Brief Bioinform
Main Authors: Baez-Ortega, Adrian, Gori, Kevin
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6357558/
https://ncbi.nlm.nih.gov/pubmed/28968631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bib/bbx082
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