Mutational signatures and mutable motifs in cancer genomes

Cancer is a genetic disorder, meaning that a plethora of different mutations, whether somatic or germ line, underlie the etiology of the ‘Emperor of Maladies’. Point mutations, chromosomal rearrangements and copy number changes, whether they have occurred spontaneously in predisposed individuals or...

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Detalhes bibliográficos
Publicado no:Brief Bioinform
Main Authors: Rogozin, Igor B, Pavlov, Youri I, Goncearenco, Alexander, De, Subhajyoti, Lada, Artem G, Poliakov, Eugenia, Panchenko, Anna R, Cooper, David N
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
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Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6454500/
https://ncbi.nlm.nih.gov/pubmed/28498882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bib/bbx049
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