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DNA polymerase η mutational signatures are found in a variety of different types of cancer
DNA polymerase (pol) η is a specialized error-prone polymerase with at least two quite different and contrasting cellular roles: to mitigate the genetic consequences of solar UV irradiation, and promote somatic hypermutation in the variable regions of immunoglobulin genes. Misregulation and mistarge...
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| Pubblicato in: | Cell Cycle |
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| Autori principali: | , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Taylor & Francis
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5914734/ https://ncbi.nlm.nih.gov/pubmed/29139326 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2017.1404208 |
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