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Mutational signatures and mutable motifs in cancer genomes

Cancer is a genetic disorder, meaning that a plethora of different mutations, whether somatic or germ line, underlie the etiology of the ‘Emperor of Maladies’. Point mutations, chromosomal rearrangements and copy number changes, whether they have occurred spontaneously in predisposed individuals or...

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Detalles Bibliográficos
Publicado en:Brief Bioinform
Main Authors: Rogozin, Igor B, Pavlov, Youri I, Goncearenco, Alexander, De, Subhajyoti, Lada, Artem G, Poliakov, Eugenia, Panchenko, Anna R, Cooper, David N
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2017
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6454500/
https://ncbi.nlm.nih.gov/pubmed/28498882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bib/bbx049
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