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β Subunit Phosphorylation Selectively Increases Fast Desensitization and Prolongs Deactivation of α1β1γ2L and α1β3γ2L GABA(A) Receptor Currents

We studied the effects of phosphorylation by protein kinase A (PKA) on GABA(A) receptors (α1β1γ2L andα1β3γ2L) transiently expressed in HEK 293T cells. Under conditions favorable for PKA activation, currents obtained using whole-cell patch clamp of lifted cells displayed increased rate and extent of...

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Bibliografiska uppgifter
I publikationen:J Neurosci
Huvudupphovsmän: Hinkle, David J., Macdonald, Robert L.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Society for Neuroscience 2003
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6740942/
https://ncbi.nlm.nih.gov/pubmed/14684872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.23-37-11698.2003
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