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Etomidate produces similar allosteric modulation in α1β3γ and α1β3γ2L GABA(A) receptors
BACKGROUND AND PURPOSE: Neuronal GABA(A) receptors are pentameric chloride ion channels, which include synaptic αβγ and extrasynaptic αβδ isoforms, mediating phasic and tonic inhibition respectively. Although the subunit arrangement of αβγ receptors is established as β-α-γ-β-α, that of αβδ receptors...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
British Journal of Pharmacology
2014
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3969089/ https://ncbi.nlm.nih.gov/pubmed/24199598 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12507 |
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