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The neurosteroid 5β-pregnan-3α-ol-20-one enhances actions of etomidate as a positive allosteric modulator of α1β2γ2L GABA(A) receptors
BACKGROUND AND PURPOSE: Neurosteroids potentiate responses of the GABA(A) receptor to the endogenous agonist GABA. Here, we examined the ability of neurosteroids to potentiate responses to the allosteric activators etomidate, pentobarbital and propofol. EXPERIMENTAL APPROACH: Electrophysiological as...
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| Vydáno v: | Br J Pharmacol |
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| Hlavní autoři: | , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
BlackWell Publishing Ltd
2014
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4294051/ https://ncbi.nlm.nih.gov/pubmed/25117207 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12861 |
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