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Calmodulin Binds to the C Terminus of Sodium Channels Na(v)1.4 and Na(v)1.6 and Differentially Modulates Their Functional Properties

Modulation of voltage-gated sodium channels (VGSC) can have a major impact on cell excitability. Analysis of calmodulin (CaM) binding to GST-fusion proteins containing the C-terminal domains of Na(v)1.1-Na(v)1.9 indicates that some of the tetrodotoxin-sensitive VGSC isoforms, including Na(V)1.4 and...

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Bibliografische gegevens
Gepubliceerd in:J Neurosci
Hoofdauteurs: Herzog, Raimund I., Liu, Chuanju, Waxman, Stephen G., Cummins, Theodore R.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Society for Neuroscience 2003
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6740705/
https://ncbi.nlm.nih.gov/pubmed/12967988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.23-23-08261.2003
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