Enhanced Evoked Excitatory Transmitter Release in Experimental Neuropathy Requires Descending Facilitation

Nerve injury-induced afferent discharge is thought to elicit spinal sensitization and consequent abnormal pain. Experimental neuropathic pain, however, also depends on central changes, including descending facilitation arising from the rostral ventromedial medulla (RVM) and upregulation of spinal dy...

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Bibliographic Details
Published in:J Neurosci
Main Authors: Gardell, L. R., Vanderah, T. W., Gardell, S. E., Wang, R., Ossipov, M. H., Lai, J., Porreca, F.
Format: Artigo
Language:Inglês
Published: Society for Neuroscience 2003
Subjects:
Behavioral/Systems/Cognitive
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6740686/
https://ncbi.nlm.nih.gov/pubmed/12967999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.23-23-08370.2003
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