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Mechanisms of Bv8-induced biphasic hyperalgesia: Increased excitatory transmitter release and expression
Bv8 is a pronociceptive peptide that binds to two G-protein coupled prokineticin receptors, PK-R1 and PK-R2. These receptors are localized in the dorsal horn of the spinal cord and dorsal root ganglia (DRG) of nociceptive neurons in rodents. Systemic administration of Bv8 elicits a biphasic reductio...
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| Publicado en: | Neurosci Lett |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2012
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5695670/ https://ncbi.nlm.nih.gov/pubmed/22641053 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2012.05.055 |
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