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Nonopioid Actions of Intrathecal Dynorphin Evoke Spinal Excitatory Amino Acid and Prostaglandin E(2) Release Mediated by Cyclooxygenase-1 and -2
Spinal dynorphin is hypothesized to contribute to the hyperalgesia that follows tissue and nerve injury or sustained morphine exposure. We considered that these dynorphin actions are mediated by a cascade involving the spinal release of excitatory amino acids and prostaglandins. Unanesthetized rats...
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| Publicado no: | J Neurosci |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Society for Neuroscience
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6730335/ https://ncbi.nlm.nih.gov/pubmed/14960618 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1517-03.2004 |
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